NCT04358952

Myocardial Involvement of Severe Acute Respiratory Syndrome-Cov-2 (Covid19) Infected Patients

Imaging Cardiac Phenotype of SARS-Cov-2 (Covid19) Infected Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 122 (actual)
• Sponsor: University Hospital, Toulouse · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The effects of severe acute respiratory syndrome SARS-Cov-2 (Covid-19) on the myocardium and their role in the clinical course of infected patients are still unknown. Epidemiological studies report biological myocardial involvement in 10 to 25% of cases. The objective of this study is to cardiac phenotype using comprehensive cardiac imaging tools of patients infected with Covid 19 in order to explore the functional impact of the infection on the myocardium.

Detailed description

A large population of Covid 19 infected patients of different ages and severity levels will be explored by transthoracic echocardiography with measurement of myocardial functional parameters such as ejection fraction, longitudinal strain and relaxation parameters and will be compared to an uninfected population paired for age and sex. Patients with biological myocardial involvement will be followed to determine the evolution of their myocardial functional parameters during the course of the infection.

Conditions

• Cardiomyopathies

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Global Longitudinal Strain	Electrocardiogram with measure of the Global Longitudinal Strain to evaluate myocardiac dysfunction

Timeline

• Start date: 2020-04-04
• Primary completion: 2021-04-02
• Completion: 2021-04-02
• First posted: 2020-04-24
• Last updated: 2021-06-01

Locations

1 site across 1 country: France