Clinical Trials Directory

Trials / Completed

CompletedNCT04358432

A Study of PCSK9 Inhibitor AK102 in Patients With Hypercholesterolemia

A Double-blind, Randomized, Placebo-controlled, Multicenter Phase II Study of AK102 in the Treatment of Hypercholesterolemia Patients at Very High or High Risk of Cardiovascular Disease

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
262 (actual)
Sponsor
Akeso · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a double-blind, randomized, placebo-controlled, multicenter study to evaluate the safety and efficacy of AK102 in patients with Hypercholesterolemia Patients at Very High or High Risk of Cardiovascular Disease . The primary objective of this study is to evaluate the efficacy of AK102 in patients with Hypercholesterolemia Patients at Very High or High Risk of Cardiovascular Disease .

Conditions

Interventions

TypeNameDescription
DRUGAK102Administered by subcutaneous injection
DRUGPlacebosAdministered by subcutaneous injection
DRUGStatins and/or EzetimibeLipid-lowering therapies

Timeline

Start date
2020-05-13
Primary completion
2021-02-25
Completion
2021-02-25
First posted
2020-04-24
Last updated
2023-03-02

Locations

2 sites across 1 country: China

Source: ClinicalTrials.gov record NCT04358432. Inclusion in this directory is not an endorsement.

A Study of PCSK9 Inhibitor AK102 in Patients With Hypercholesterolemia (NCT04358432) · Clinical Trials Directory