NCT04357015

Intravenous Tranexamic Acid Versus IV Carbetocin in Abdominal Myomectomy

Comparative Safety and Efficacy of Intravenous Tranexamic Acid Versus IV Carbetocin in Reducing Blood Loss During Abdominal Myomectomy: a Randomized Controlled Trial

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 153 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

the aim of the present study is to compare safety and efficacy of intravenous tranexamic acid versus IV carbetocin in reducing blood loss during abdominal myomectomy: a randomized controlled trial

Conditions

• Myomectomy

Interventions

Type	Name	Description
DRUG	intravenous tranexamic acid	The tranexamic acid (TXA) group will receive a single bolus IV injection of 15 mg/kg of TXA 20 minutes before surgical incision
DRUG	intravenous carbetocin	The carbetocin group will receive a single bolus IV injection of 100 mcg of carbetocin 20 minutes before surgical incision
DRUG	placebo	the placebo group will be given a normal saline IV bolus 20 minutes before surgical incision

Timeline

• Start date: 2020-05-01
• Primary completion: 2020-10-10
• Completion: 2020-10-20
• First posted: 2020-04-22
• Last updated: 2020-04-22