Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT04356677

Study to Evaluate the Safety and Efficacy of VIRAZOLE® in Hospitalized Adult Participants With Respiratory Distress Due to COVID-19_#2

An Open-Label Study to Evaluate the Safety and Efficacy of VIRAZOLE® (RIBAVIRIN FOR INHALATION SOLUTION, USP) in Hospitalized Adult Participants With Respiratory Distress Due to COVID-19

Status
Withdrawn
Phase
Phase 1
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Bausch Health Americas, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study is a Phase 1, open label, non-randomized, two-arm interventional clinical trial to evaluate the safety and efficacy of Virazole® in hospitalized adult patients who have tested positive for COVID-19 and, as a result, have significant respiratory distress (PaO2/FiO2 ratio \<300 mmHg).

Conditions

Interventions

TypeNameDescription
DRUG50 mg/mL Virazole50 mg/mL Virazole aerosolized and administered over 1 hour twice a day for up to 6 days.
DRUG100 mg/mL Virazole100 mg/mL Virazole aerosolized and administered over 30 minutes twice a day for up to 6 days.

Timeline

Start date
2021-05-01
Primary completion
2021-08-01
Completion
2021-08-01
First posted
2020-04-22
Last updated
2025-09-16

Source: ClinicalTrials.gov record NCT04356677. Inclusion in this directory is not an endorsement.