Trials / Completed
CompletedNCT04356573
(KIWI) Speeding up a Slow Protein for Muscle Mass With Hay Kiwifruit
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 13 (actual)
- Sponsor
- University of Arkansas · Academic / Other
- Sex
- All
- Age
- 60 Years – 85 Years
- Healthy volunteers
- Accepted
Summary
The specific hypothesis is that the consumption of 2 Hayward green kiwifruit (containing actinidin protease) prior to 100g of ground beef will increase the rate of protein digestion from the beef in the elderly, leading to an increased uptake of the essential amino acids. Furthermore, this increased essential amino acid availability will produce a greater postprandial net anabolic protein response, as well as increased fractional synthetic rates of muscle proteins.
Detailed description
The specific hypothesis is that the consumption of 2 Hayward green kiwifruit (containing actinidin protease) prior to 100g of ground beef will increase the rate of protein digestion from the beef in the elderly, leading to an increased uptake of the essential amino acids. Furthermore, this increased essential amino acid availability will produce a greater postprandial net anabolic protein response, as well as increased fractional synthetic rates of muscle proteins. To test this hypothesis, the investigators will use a double-blinded crossover design involving two intervention arms; in both arms 100g of ground beef (cooked weight) will be consumed following either 2 Hayward green kiwifruit (containing actinidin protease) or 2 Hort16A Gold kiwifruit (devoid of actinidin protease) by elderly subjects.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Green Hayward Kiwifruit first, then Gold Kiwifruit | Subjects ate 2 peeled green kiwifruit with their midday meal for 2 weeks prior to testing. |
| DIETARY_SUPPLEMENT | Gold Kiwifruit First, then Green Hayward Kiwifruit | Subjects ate 2 peeled gold kiwifruit with their midday meal for 2 weeks prior to testing. |
Timeline
- Start date
- 2018-07-01
- Primary completion
- 2018-11-20
- Completion
- 2018-11-20
- First posted
- 2020-04-22
- Last updated
- 2021-11-04
- Results posted
- 2021-11-04
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT04356573. Inclusion in this directory is not an endorsement.