NCT04356183

Weight Loss and Exercise To Improve Rheumatoid Arthritis Cardiovascular Risk

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Duke University · Academic / Other
• Sex: All
• Age: 60 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This is a small exploratory, randomized, controlled trial. Twenty-six older (ages 60-80 yr.), obese (BMI 28-40 kg/m2) persons with rheumatoid arthritis (RA) (seropositive or erosive) will be randomized to 16 weeks of a counseling health as treatment (CHAT) program or a supervised weight loss and exercise training (SWET) program.

Conditions

• Rheumatoid Arthritis

Interventions

Type	Name	Description
OTHER	SWET: Supervised Weight loss and Exercise Training	Weight loss will occur via a dietitian-led intervention targeting weight loss over 16 weeks, with weekly weigh-ins and group support sessions. Exercise training will consist of three times per week of an interval-based aerobic program plus twice-weekly resistance training. Both weight loss and exercise training will be supervised to maximize safety and adherence.
OTHER	CHAT: Counseling Health As Treatment	Control Arm over 16 weeks.

Timeline

• Start date: 2021-07-21
• Primary completion: 2023-02-03
• Completion: 2023-02-23
• First posted: 2020-04-22
• Last updated: 2025-03-30
• Results posted: 2024-03-08

Locations

1 site across 1 country: United States