Trials / Completed
CompletedNCT04356105
Protocols of IVF/ICSI in Poor Responders
Minimal Stimulation in a Combined Letrozole Antagonist Protocol Versus Microflare Protocol in Poor Responders Undergoing Invitrofertilization/ Intracytoplasmic Sperm Injection; Randomized Parallel Study
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 132 (actual)
- Sponsor
- Cairo University · Academic / Other
- Sex
- Female
- Age
- 30 Years – 43 Years
- Healthy volunteers
- Accepted
Summary
Comparing two ovarian induction protocols in poor responders in IVF/ICSI cycles
Detailed description
The two groups of poor responders are randomized into either; a minimal dose stimulation protocol involving letrozole, recombinant FSH and GnRH antagonist versus a microflare conventional protocol with OCP, GnRH agonist and high dose recombinant FSH, in their IVF/ICSI cycles, primary outcome will be the number of oocytes retrieved.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Minimal stimulation protocol | Letrozole, Recombinant FSH, GnRH antagonist |
| DRUG | Microflare protocol | OCP, GnRH agonist, Recombinant FSH |
| PROCEDURE | IVF/ICSI cycle | Involving ovum pickup and embryo transfer |
Timeline
- Start date
- 2020-06-01
- Primary completion
- 2021-09-30
- Completion
- 2021-10-31
- First posted
- 2020-04-22
- Last updated
- 2021-11-16
Locations
2 sites across 1 country: Egypt
Source: ClinicalTrials.gov record NCT04356105. Inclusion in this directory is not an endorsement.