Trials / Completed
CompletedNCT04355741
Gut Microbiota, "Spark and Flame" of COVID-19 Disease
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 115 (actual)
- Sponsor
- Universidade Nova de Lisboa · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Elderly, hypertension, diabetes and cardiovascular diseases are risk factors for COVID-19 morbility and mortality. However, the real reason for this is not yet understood. It is well documented that gut microbiota has a critical role in health, particularly in the immune system and therefore, we propose that gut microbiota composition could affect vulnerability and disease outcomes of COVID-19.
Detailed description
In order to explore this hypothesis, we will analyse the gut microbiota of SARSCoV-2 infected patients categorized according to location: \[1\] ambulatory (self-isolation at home), \[2\] ward and \[1\] ICU; and severity.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Exposure | Individuals with SARS-CoV-2 exposure and COVID-19 symptoms. |
Timeline
- Start date
- 2020-04-20
- Primary completion
- 2020-07-01
- Completion
- 2020-07-16
- First posted
- 2020-04-21
- Last updated
- 2020-08-25
Locations
3 sites across 1 country: Portugal
Source: ClinicalTrials.gov record NCT04355741. Inclusion in this directory is not an endorsement.