NCT04353947

Induction and Recognition of Emotions

Induction and Recognition of Emotions in Healthy Older Adults, Alzheimer's Disease and Parkinson's Disease

• Status: Withdrawn
• Phase: —
• Study type: Observational
• Enrollment: 0 (actual)
• Sponsor: University of Valencia · Academic / Other
• Sex: All
• Age: 65 Years – 99 Years
• Healthy volunteers: Accepted

Summary

This study evaluates the differences in cognitive function between healthy older adults, older adults with mild Alzheimer's type dementia and older adults with Parkinson's disease and if there are differences in valence assessment and activation that produce them a mood induction task. Subjects are assessed using neuropsychological tests and then a mood induction task based on movie clips is applied.

Detailed description

Different neuropsychological tests will be used to assess the differences in cognitive function in the different groups, whose scores are expected to be lower in the group of older adults with Alzheimer's disease (AD) and older adults with Parkinson's disease (PD). After studying the cognitive function in the different groups, we proceed to check through a task based on movie clips if there are also differences in the valence assessment (liking/disliking depending on the emotion induced by scenes from different films) and activation (excitement caused by each one of the movie scenes), hoping to find differences for the negative emotions taking into account the cognitive difficulties that both (the EA group and the EP group) may have for processing this type of cognitively more demanding information; instead, it is possible that the positivity effect continues to affect these patients so that for positive emotions there are no differences between the different groups.

Conditions

• Healthy Older Adults
• Alzheimer's Disease
• Parkinson's Disease

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Mini Cognitive Examination (MCE)	This test provides information on temporal and spatial orientation, fixation, concentration and calculation, memory and language and construction.
DIAGNOSTIC_TEST	Beck Depression Inventory-II (BDI-II)	This test evaluates the absence or presence of depressive symptoms.
DIAGNOSTIC_TEST	Global Deterioration Scale (GDS)	This scale measures the level of deterioration of the subject.
DIAGNOSTIC_TEST	Memory alteration test (M@T)	In this test different memory subtypes are evaluated.
DIAGNOSTIC_TEST	Spanish-Complutense Verbal Learning Test (TAVEC)	This test is used to assess immediate memory, deferred memory and learning ability.
DIAGNOSTIC_TEST	Barcelona test (BT)	This test evaluates categorical evocation and verbal fluency. The categorical recall subtest consists of recalling the maximum number of words linked to a specific category "animals" in 1 minute. In the case of verbal fluency, the subject is asked to evoke the maximum number of words that begin with the letter "p" in 3 minutes.
DIAGNOSTIC_TEST	Rey-Osterrieth Complex Figure Test (ROCFT)	In this test, the person must carefully copy a complex geometric drawing, which must be memorized later. The first part evaluates multiple cognitive processes such as planning, motor skills, working memory, and visual-constructive and spatial skills. In the second part, memory is evaluated.
DIAGNOSTIC_TEST	Frontal assessment battery (FAB)	This test is a composite tool for assessing executive functions related to the frontal lobe.
DIAGNOSTIC_TEST	Positive and Negative Affect Scale (PANAS)	It is a self-report questionnaire made up of 20 items (10 of positive affect and another 10 of negative affect) that the subject must answer, obtaining in this way a score in positive affectivity (AP subscale) and another in negative affectivity (AN subscale).
DIAGNOSTIC_TEST	Auto-Assessment Manikins (SAM)	It is a self-report questionnaire that assesses the emotional response of the subject, in this case, through a mood induction task that plays different films scenes.

Timeline

• Start date: 2020-03-02
• Primary completion: 2020-10-30
• Completion: 2020-11-30
• First posted: 2020-04-21
• Last updated: 2021-05-06

Locations

1 site across 1 country: Spain