NCT04353063

Muscle Wasting in Children and Adolescents With Cancer

Assessment and Management of Muscle Wasting in Children and Adolescents With Cancer

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 440 (estimated)
• Sponsor: National Taiwan University Hospital · Academic / Other
• Sex: All
• Age: 3 Years – 18 Years
• Healthy volunteers: Not accepted

Summary

The series of the 3-year study aims to explore parents' experience of caring for a child's weight change among parents of children and adolescents with cancer, examine the associations and trends among muscle wasting and health-related variables, and then implement and assess effectiveness of a multidisciplinary approach with a personalized physical activity (walking) training intervention on improving muscle mass and other health-related variables.

Detailed description

Specific aims, year by year 1. The aim for Year 1 is as follows: Aim 1: To explore parents' experience of caring for promoting a child's exercise among parents of children and adolescents with cancer. 2. The aims for Year 2 are as follows: Aim 2-1: To examine the associations between the degree of muscle wasting and health-related variables (fatigue level, symptom distress level, physical activity involvement, dietary intake, and QoL) among children and adolescents with cancer. Aim 2-2: To examine the trends of changes in muscle wasting and health-related variables (fatigue level, symptom distress level, physical activity involvement, dietary intake, and QoL) during the first 6 months of cancer treatment among children and adolescents with cancer. 3. The aim for Year 3 is as follows: Aim 3: To examine the effectiveness of a multidisciplinary approach with a personalized walking exercise program on changes in body composition and health-related variables (fatigue level, symptom distress level, subjective physical activity involvement, objective physical activity measurement, dietary intake, and QoL) among children and adolescents with cancer.

Conditions

• Cachexia; Cancer
• Muscle Wasting
• Child Development
• Adolescent Development

Interventions

Type	Name	Description
BEHAVIORAL	Multidisciplinary care with a personalized care	During the 4-week intervention, participants will be given stickers by the research assistant to increase their motivation to walk. A sticker will be given once a participant reaches a daily walking-time goal. The number of stickers participants receive depends on the number of days they reach their daily goals. The stickers can be redeemed for the participant's choice of gift in the gift shelf of the ward or on a gift card. A final assessment will be conducted at week 4. The participant will be reminded that the ActiGraph and the post-test questionnaires will be picked up at the end of week 4

Timeline

• Start date: 2020-08-14
• Primary completion: 2023-07-31
• Completion: 2023-07-31
• First posted: 2020-04-20
• Last updated: 2020-09-09

Locations

1 site across 1 country: Taiwan