NCT04352504

The Effect of a Healthy Snack on Radiance, Aging and Inflammation of the Skin

Clinical Trial to Determine the Efficacy of Almonds for Skin Radiance, Inflammation and Aging in Asian Females: A Pilot Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: University of California, Los Angeles · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The anti-oxidative and anti-inflammatory effects of polyphenolic compounds of almonds have been reported in limited animal studies and may have the potential to improve skin radiance. However, the skin related beneficial properties of almonds have not been investigated in humans. This study will examine the effects of almond consumption on human skin radiance in Asian women as a pilot.

Detailed description

This study is a randomized, parallel group comparison of almonds vs. isocaloric pretzels carried out in accordance with the guidelines of the Human Subjects Protection Committee of the University of California, Los Angeles. All subjects will give written informed consent before the study begins. Subjects will consume 1.5 serving of almonds (\~ 1.5 oz/d for 246kcal) or isocaloric pretzels (\~ 2.0 oz/d for 216kcal) daily for 12 weeks and will undergo skin assessment at weeks 0, 4, 8 and 12. The assessments include skin radiance, sebum, and hydration/moisture. In addition the study will evaluate the effect of almond consumption on skin inflammation and aging by assessing UV-induced changes. Each group will have 20 subjects.

Conditions

• Skin Laxity

Interventions

Type	Name	Description
OTHER	Almond	Consume 1.5 oz. serving almonds (246 calories) daily for 12 weeks
OTHER	Pretzel	Consume 2 oz. serving of pretzels (216 calories) daily for 12 weeks

Timeline

• Start date: 2019-07-25
• Primary completion: 2020-01-23
• Completion: 2020-01-23
• First posted: 2020-04-20
• Last updated: 2020-04-20

Locations

1 site across 1 country: United States