NCT04352088

Immune Response Features in Allergic Airway Diseases

Investigation of Phenotypes, Endotypes and Immune Response Features in Allergic Airway Diseases

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 150 (estimated)
• Sponsor: Lithuanian University of Health Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This study aims to investigate immune mechanisms and phenotypes and endotypes of allergic airway diseases - allergic rhinitis and allergic asthma. Pathogenesis of these diseases are not fully investigated yet. Patients with the same disease have different dominant symptoms, course of the disease and response to treatment. Moreover, there is a hypothesis about united airway disease suggesting that allergic rhinitis and allergic asthma is different manifestation of the same disease. This led to assumption of phenotypes and endotypes. This classification which still is not unified can let to prescribe personalized treatment for every patient.

Conditions

• Allergic Rhinitis
• Allergic Asthma

Interventions

Type	Name	Description
PROCEDURE	Nasal provocation test	Allergen extract under controlled conditions will be applied into nasal mucous.

Timeline

• Start date: 2019-05-01
• Primary completion: 2022-11-01
• Completion: 2024-04-01
• First posted: 2020-04-17
• Last updated: 2020-04-17

Locations

1 site across 1 country: Lithuania