NCT04351672

Time-restricted Feeding as a Dietary Strategy Against Metabolic Disturbances in Humans

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 31 (actual)
• Sponsor: German Institute of Human Nutrition · Academic / Other
• Sex: Female
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This human dietary intervention study with a cross-over design aims to compare the effects of two isocaloric diets - early time-restricted feeding (TRF) vs. late TRF - on glycemic control and lipid metabolism in overweight and obese women.

Detailed description

The participants are randomly allocated to one of two study groups: In study group (A) participants will begin with the early TRF (e-TRF) intervention. They will consume their habitual food (and the habitual daily amount of food) between 8 am and 4 pm for two weeks. After a washout-phase participants will conduct the late TRF (l-TRF) and consume their habitual food between 1 pm and 9 pm for another two weeks. Study group (B) receives the same interventions in the reversed order. Both dietary regimens will result in 8-hr eating period and 16-hr fasting period during the 24h day.

Conditions

• Overweight and Obesity

Interventions

Type	Name	Description
BEHAVIORAL	Early Time-Restricted Feeding	Eat between 8 am and 4 pm for two weeks
BEHAVIORAL	Late Time-Restricted Feeding	Eat between 1 pm and 9 pm for two weeks

Timeline

• Start date: 2020-06-23
• Primary completion: 2021-12-20
• Completion: 2023-02-28
• First posted: 2020-04-17
• Last updated: 2024-08-26

Locations

1 site across 1 country: Germany