NCT04350307

Comparison of Intravascular Uptake and Pain Perception During Epidural Injection Using 22 Gauge vs 25 Gauge Needle

Differential Rates of Intravascular Uptake and Pain Perception During Lumbosacral Transforaminal Epidural Steroid Injection Using a 22-gauge Needle Versus 25-gauge Needle

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 162 (actual)
• Sponsor: Yale University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study was to quantify the difference between a 22-gauge needle and 25-gauge needle during lumbosacral epidural steroid injection in regards to intravascular uptake and pain perception. There is the notion that a smaller gauge needle may lead to less intravascular uptake and less pain.

Detailed description

Inadvertent intravascular injection has been suggested as the most probable mechanism behind serious neurological complications during transforaminal epidural steroid injections. There is the notion that a smaller gauge needle may lead to less intravascular uptake and less pain. The aim of the study was to quantify the difference between a 22-gauge needle and 25-gauge needle during lumbosacral transforaminal epidural steroid injection in regards to intravascular uptake and pain perception.

Conditions

• Pain
• Needle Injury

Interventions

Type	Name	Description
DEVICE	22-gauge needle	22-gauge Quincke needle used for epidural injection
DEVICE	25-gauge needle	25-gauge Quincke needle used for epidural injection

Timeline

• Start date: 2018-02-01
• Primary completion: 2019-06-30
• Completion: 2019-09-30
• First posted: 2020-04-17
• Last updated: 2020-07-20
• Results posted: 2020-07-20

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study