Clinical Trials Directory

Trials / Terminated

TerminatedNCT04349956

Long-Term Follow-Up Study of Patients With Osteoarthritis of the Knee Treated With UBX0101 or Placebo

Long-Term Follow-Up Study of Patients With Moderate to Severe, Painful Osteoarthritis of the Knee Who Participated in a Randomized, Placebo-Controlled Study of UBX0101

Status
Terminated
Phase
Study type
Observational
Enrollment
161 (actual)
Sponsor
Unity Biotechnology, Inc. · Industry
Sex
All
Age
40 Years – 85 Years
Healthy volunteers
Not accepted

Summary

A follow-up study to assess the long-term safety of intra-articular (IA) administration of UBX0101 in patients with painful knee osteoarthritis (OA).

Detailed description

This is a blinded, multi-center study to provide approximately 1 additional year of follow-up for patients with knee OA who participated in a randomized placebo-controlled study of IA UBX0101. No intervention is planned and patients will have 4 scheduled visits to collect follow-up assessments. The primary objective is to evaluate long-term safety and tolerability of IA administration of UBX0101 in patients with painful knee OA.

Conditions

Interventions

TypeNameDescription
DRUGUBX0101 or placeboThis is an observational study. No intervention is administered.

Timeline

Start date
2020-04-20
Primary completion
2020-11-02
Completion
2020-11-02
First posted
2020-04-16
Last updated
2020-11-17

Locations

17 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04349956. Inclusion in this directory is not an endorsement.