Trials / Recruiting
RecruitingNCT04343443
Acute Heart Failure With Reduced Ejection Fraction - COngestion Discharge Evaluation
Acute Heart Failure With Reduced Ejection Fraction - COngestion Discharge Evaluation: Evaluation de la Congestion à la Sortie d'Hospitalisation Pour Insuffisance Cardiaque aiguë à Fraction d'éjection altérée ou modérément altérée
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- Sponsor
- Central Hospital, Nancy, France · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The AHF-CODE reduced study is a prospective, non-randomized, monocenter study performed in patients with heart failure with reduced ejection fraction admitted for worsening heart failure. The main objective of the AHF-CODE study is to identify congestion markers (clinical, biological and ultrasound) at the end of hospitalization for acute heart failure that are associated with the risk of all cause death or rehospitalization for acute heart failure within 3 months of hospital discharge.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Clinical examination centered on congestion | Clinical examination centered on congestion (ASCEND, NYHA and Ambrosy Score) will be performed before discharge from hospital |
| PROCEDURE | Cardio-pulmonary, peritoneal, jugular and renal Doppler ultrasounds and liver elastography | Cardio-pulmonary, peritoneal, jugular and renal Doppler ultrasounds and liver elastography will be performed before discharge from hospital |
| PROCEDURE | Biological: Blood sample retrieved for biological assessment and biobanking | Blood sample collection will be performed before discharge from hospital |
| PROCEDURE | Telephone interview | Telephone interview will be performed at 3, 12 months and 24 months after discharge from hospital |
| BEHAVIORAL | Kansas City Cardiomyopathy Questionnaire (KCCQ) | Questionnaire centered on patient's quality of life at discharge and 3, 12 and 24 months after discharge |
Timeline
- Start date
- 2020-08-21
- Primary completion
- 2026-08-21
- Completion
- 2028-08-21
- First posted
- 2020-04-13
- Last updated
- 2023-06-05
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT04343443. Inclusion in this directory is not an endorsement.