NCT04340440

Curative D2 vs D1 Lymphadenectomy in Operable Gastric Carcinoma

Surgical and Oncologic Outcomes After Curative D2 vs D1 Gastrectomy in Operable Gastric Carcinoma, A Randomized Controlled Study in Egyptian Population

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: University of Alexandria · Academic / Other
• Sex: All
• Age: 20 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Gastric carcinoma is the second most common cause of cancer-related deaths and its main treatment modality if potentially curable is surgery but the optimal surgical resection is controversial. The aim of the current study was to assess the outcomes of curative D2 compared to D1 gastrectomy of operable gastric carcinoma regarding postoperative morbidity and mortality, disease recurrence and survival rates.

Detailed description

80 consecutive patients with potentially operable gastric carcinoma were randomized via concealed envelopes into 2 groups (each included 40 patients), group I managed by radical gastrectomy with D1 lymphadenectomy while group II managed by radical gastrectomy with D2 lymphadenectomy . Both groups were compared regarding postoperative mortality, morbidities, tumor recurrence and 2 years survival rates.

Conditions

• Gastric Cancer

Interventions

Type	Name	Description
PROCEDURE	D1 lymphadenectomy	Radical gastrectomy with D1 lymphadenectomy
PROCEDURE	D2 lymphadenectomy	Radical gastrectomy with D2 lymphadenectomy

Timeline

• Start date: 2014-12-01
• Primary completion: 2017-09-01
• Completion: 2020-02-01
• First posted: 2020-04-09
• Last updated: 2020-04-10