Clinical Trials Directory

Trials / Terminated

TerminatedNCT04339595

Long-Term Treatment Effect With Tildrakizumab in Participants With Plaque Psoriasis

A Phase IV Interventional Study to Assess the Disease-Modifying Effect of Long-Term Treatment With Tildrakizumab in Adult Patients With Moderate-To-Severe Plaque Psoriasis (MODIFY)

Status
Terminated
Phase
Phase 4
Study type
Interventional
Enrollment
47 (actual)
Sponsor
Almirall, S.A. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the psoriasis disease control over time in participants who had received Tildrakizumab for at least the last 5 years and have discontinued it and to describe blood and skin inflammatory biomarkers and its correlation disease relapse.

Conditions

Interventions

TypeNameDescription
BIOLOGICALTildrakizumabParticipants who have participated and completed the long-term extension phase of the reSURFACE 2 study (NCT01729754) and 12 weeks after the last Tildrakizumab dose will be included in the present study. Participants will not receive any study medication during the present study. Participants will remain in the study for 96 weeks or until they initiate any systemic therapy for psoriasis (including phototherapy), whichever occurs first.

Timeline

Start date
2020-01-29
Primary completion
2020-07-31
Completion
2020-07-31
First posted
2020-04-09
Last updated
2021-12-08

Locations

3 sites across 1 country: Poland

Source: ClinicalTrials.gov record NCT04339595. Inclusion in this directory is not an endorsement.