NCT04339049

Comparative Efficacy of Lidocaine Spray Versus Vaginal Misoprostol in IUD Insertion

Comparative Efficacy of Lidocaine Spray Versus Vaginal Misoprostol in Reducing Pain During IUD Insertion in Adolescents and Nulliparous Women: a Randomized Controlled Trial

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 147 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Accepted

Summary

the aim of the present study is to compare the safety and efficacy of lidocaine spray versus misoprostol in reducing pain during IUD insertion in adolescents and nulliparous women

Conditions

• Contraception

Interventions

Type	Name	Description
DRUG	lidocaine spray	four puffs (10 mg/puff) of lidocaine spray before tenaculum placement plus vaginal placebo 3 hours before IUD insertion
DRUG	vaginal misoprostol	vaginal misoprostol 200 mcg given 3 hours before IUD insertion plus four puffs of saline spray before tenaculum placement
DRUG	placebo	vaginal placebo given 3 hours before IUD insertion plus four puffs of saline spray before tenaculum placement

Timeline

• Start date: 2020-05-01
• Primary completion: 2021-07-17
• Completion: 2021-07-30
• First posted: 2020-04-08
• Last updated: 2021-12-10

Locations

1 site across 1 country: Egypt