Trials / Unknown
UnknownNCT04337008
Renin Angiotensin System - CoronaVirus
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- Sponsor
- Assistance Publique Hopitaux De Marseille · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The aim of the study is to demonstrate overactivation of Renin Angiotensine System (RAS) in positives COVID-19 patient, especially in those with the most serious clinical forms where the mortality of patients in intensive care is on average 50%. We are expecting two groups: a group of 25 positive COVID 19 patients in intensive care and a group of 25 positive COVID 19 hospitalized patients in conventional hospitalisation. We will measure RAS, serum potassium and collect data on the treatment of these patients (especially antihypertensive therapy) one week apart (at the patient'entry into hospital and 7 days later). This is a preliminary study that could possibly allow the start of a therapeutic trial in order to test the effectiveness of RAS blocker treatments in this condition.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | blood draw | 20 mL blood draw will be performed at J1 et J7 |
Timeline
- Start date
- 2020-04-03
- Primary completion
- 2020-06-03
- Completion
- 2020-07-31
- First posted
- 2020-04-07
- Last updated
- 2020-04-24
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT04337008. Inclusion in this directory is not an endorsement.