Trials / Completed
CompletedNCT04335526
A Clinical Study to Assess the Effect of Change of Bile Acid on the PD and Safety of Metformin and Microbiome Profiles
A Clinical Study for Assessing the Effect of Change of Bile Acid Pool on the Pharmacodynamics and Safety of Metformin and Intestinal Microbiome Profiles in Healthy Volunteers
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 15 (actual)
- Sponsor
- Seoul National University Hospital · Academic / Other
- Sex
- Male
- Age
- 19 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
This clinical trial is intended to evaluate the effect of change of bile acid pool with cholestyramine on the pharmacodynamics and safety of metformin and intestinal microbiome profiles in healthy volunteers
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Cholestyramine Resin | Change bile acid pool by cholestyramine treatment |
Timeline
- Start date
- 2020-05-01
- Primary completion
- 2020-07-30
- Completion
- 2020-10-21
- First posted
- 2020-04-06
- Last updated
- 2021-03-17
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT04335526. Inclusion in this directory is not an endorsement.