Clinical Trials Directory

Trials / Completed

CompletedNCT04335136

Recombinant Human Angiotensin-converting Enzyme 2 (rhACE2) as a Treatment for Patients With COVID-19

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
185 (actual)
Sponsor
Apeiron Biologics · Industry
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

Recombinant human angotensin-converting enzyme 2 (rhACE2) as a treatment for patients with COVID-19 to block viral entry and decrease viral replication.

Conditions

Interventions

TypeNameDescription
DRUGRhACE2 APN01Patients will be treated with APN01 intravenously twice daily (BID).
DRUGPhysiological saline solutionPatients will be treated with placebo intravenously twice daily (BID).

Timeline

Start date
2020-04-30
Primary completion
2020-12-26
Completion
2020-12-26
First posted
2020-04-06
Last updated
2021-08-02
Results posted
2021-08-02

Locations

22 sites across 5 countries: Austria, Denmark, Germany, Russia, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT04335136. Inclusion in this directory is not an endorsement.