NCT04334603

EXercise InTervention in Heart Failure

EXercise InTervention in Heart Failure (EXIT-HF): a Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Centro Hospitalar do Porto · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a pragmatic, non-inferiority clinical trial, enrolling heart failure patients who will be randomized to a 12-week exercise training program either centre-based or home-based with telemonitoring. The impact of this intervention will be assessed on established surrogate markers in HF such as maximal exercise capacity, plasma biomarkers and quality of life. The cost-effectiveness and overall satisfaction with the treatment will also be studied. In addition to measure the clinical and economic impact of this innovative way of delivering exercise, it is intended to unravel new molecular pathways and assess a pool of biomarkers that provide a wide mechanistic picture underlying the clinical effects of exercise.

Conditions

• Heart Failure

Interventions

Type	Name	Description
OTHER	Exercise Training Program	The 12-week exercise-training program will include two sessions of combined exercise training per week, performed at the hospital or at home.

Timeline

• Start date: 2019-11-01
• Primary completion: 2022-12-30
• Completion: 2022-12-30
• First posted: 2020-04-06
• Last updated: 2023-02-23

Locations

1 site across 1 country: Portugal