Trials / Recruiting
RecruitingNCT04332692
Acute Heart Failure - COngestion Discharge Evaluation
Acute Heart Failure - COngestion Discharge Evaluation. Évaluation de la Congestion à la Sortie d'Hospitalisation Pour Insuffisance Cardiaque aiguë.
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 110 (estimated)
- Sponsor
- Central Hospital, Nancy, France · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Acute heart failure (AHF) is a major public health problem, associated with a 40% risk of death or re-hospitalisation at 3 months. This risk is significantly increased by insufficient decongestion at the end of hospitalisation for AHF assessed by a standardised clinical score, a natriuretic peptide dosage or by cardiac and pulmonary ultrasound . Adapting treatment according to lung congestion assessed by implantable devices (not reimbursed in France) improves the prognosis. However, due to the lack of a standardised congestion assessment, therapeutic adaptation in acute heart failure is currently empirical. The best multimodality approach to congestion evaluation is uncertain.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Clinical examination centered on congestion | Clinical examination centered on congestion (ASCEND, NYHA and Ambrosy Score) will be performed before discharge from hospital |
| PROCEDURE | Cardiac, pulmonary, peritoneal, jugular, renal Doppler ultrasounds and liver elastography | Cardiac, pulmonary, peritoneal, jugular and renal Doppler ultrasounds and liver elastography will be performed before discharge from hospital |
| PROCEDURE | Blood sample retrieved for biological assessment and biobanking | Blood sample retrieved for biological assessment and biobanking will be performed before discharge from hospital |
| PROCEDURE | Telephone follow-up | Telephone follow-up will be performed 3, 12 and 24 months after discharge from hospital |
| BEHAVIORAL | Kansas City Cardiomyopathy Questionnaire (KCCQ) | Questionnaire centered on patient's quality of life at discharge and 3, 12 and 24 months after discharge |
Timeline
- Start date
- 2020-07-15
- Primary completion
- 2026-08-20
- Completion
- 2028-05-20
- First posted
- 2020-04-03
- Last updated
- 2023-06-05
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT04332692. Inclusion in this directory is not an endorsement.