Clinical Trials Directory

Trials / Recruiting

RecruitingNCT04332367

Carboplatin, Taxane And Ramucirumab for Patients With NSCLC After Pemetrexed or Pembrolizumab Maintenance

Phase II, Single-Arm Study Of Carboplatin, Weekly Taxane, And Ramucirumab In Advanced Non-Squamous Non-Small Cell Lung Cancer (NSCLC) After Progressive Disease On Maintenance Pemetrexed And/Or Pembrolizumab

Status
Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
59 (estimated)
Sponsor
Abramson Cancer Center at Penn Medicine · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine if the combination of the three anti-cancer drugs carboplatin, paclitaxel, and ramucirumab is helpful in shrinking tumors or delaying tumor growth in participants with non-small cell lung cancer. This study will also assess whether it is safe to combine these drugs.

Conditions

Interventions

TypeNameDescription
DRUGCarboplatinCarboplatin IV
DRUGPaclitaxelPaclitaxel IV
DRUGRamucirumabRamucirumab IV

Timeline

Start date
2020-08-01
Primary completion
2026-04-01
Completion
2026-04-01
First posted
2020-04-02
Last updated
2026-01-07

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04332367. Inclusion in this directory is not an endorsement.