NCT04331314

Biphasic Calcium Phosphate vs. Hydroxyapatite in Sinus Floor Elevation

Sinus Augmentation Using Symbios Versus Algipore as Bone Graft Material - A Randomized Controlled Clinical Pilot Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Medical University of Graz · Academic / Other
• Sex: All
• Age: 20 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Twenty patients scheduled for lateral-window sinus floor Elevation (SFE) are randomized into two groups: use of SYMBIOS® Biphasic Bone Graft Material (Group 1) or of Algipore® Bone Substitution Material (Group 2). Biopsies are taken 3 months after SFE and during implant surgery after 6 months. One ground section per biopsy (n=40) is stained, scanned, and histomorphometrically analyzed for new bone, old bone, soft tissue, graft, bone infiltration of graft, bone-to-graft contact, and penetration depth.

Conditions

• Bone Substitutes
• Calcium Phosphates
• Hydroxyapatite
• Rhodophyta
• Sinus Floor Augmentation

Interventions

Type	Name	Description
DEVICE	Use of Symbios Bone Graft Material	Patients will receive Symbios Bone Graft Material according to randomization Group.
DEVICE	Algipore Bone Substitution Material	Patients will receive Algipore Bone Substitution Material according to randomization Group.

Timeline

• Start date: 2015-02-23
• Primary completion: 2018-03-20
• Completion: 2019-10-28
• First posted: 2020-04-02
• Last updated: 2020-04-02