Trials / Unknown
UnknownNCT04329260
Mutation of the LEPR Gene at Reunion Island: Involvement in Pediatric Obesity
Mutation of the LEPR Gene at Reunion Island: Involvement in Pediatric Obesity GRÉOL (Génétique Réunion Obésité LEPR)
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 250 (estimated)
- Sponsor
- Centre Hospitalier Universitaire de la Réunion · Academic / Other
- Sex
- All
- Age
- 3 Years – 18 Years
- Healthy volunteers
- Not accepted
Summary
The objective of this study is to estimate the proportion of the recurrent deletion Δ6-8 of the LEPR gene in the homozygous and heterozygous state in pediatric cases with severe and early ( before the age of 6) obesity (BMI ≥ IOTF-30) on Reunion Island.
Detailed description
The study of the deletion Δ6-8 of the LEPR gene starts with a saliva sample using a swab in children aged between 3 to 18 years old. The DNA from this sample will then be analyzed by the PCR technique. If the deletion of the LEPR gene is confirmed in the patient, his adult family members will also be screened using the same procedure.
Conditions
Timeline
- Start date
- 2021-03-01
- Primary completion
- 2022-06-01
- Completion
- 2022-12-01
- First posted
- 2020-04-01
- Last updated
- 2021-01-27
Source: ClinicalTrials.gov record NCT04329260. Inclusion in this directory is not an endorsement.