NCT04327752

Skin Adverse Reactions Occuring in Children Treated by Biotherapy for Chronic Inflammatory Disease

Cutaneous Adverse Effects Occurring in Children Under Biological Therapy Given for Chronic Inflammatory Diseases

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 20 (actual)
• Sponsor: Centre Hospitalier Universitaire, Amiens · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Biological treatments (BT) are commonly prescribed to treat chronic inflammatory diseases in children. Paradoxical reactions during treatment with a biological agent can be defined as the appearance or exacerbation of a pathological condition that usually responds to this class of drug while treating a patient for another condition. Limited data are available in children treated by BT on cutaneous paradoxical reactions, or any other cutaneous adverse events occurring during treatment. On the contrary, dermatologists tend to see and manage increasing numbers of cutaneous adverse events, including paradoxical reactions. The aim of this project is to describe the incidence of cutaneous adverse events, including cutaneous paradoxical reactions, occurring in the pediatric population, during a treatment by BT given for a chronic inflammatory disease.

Conditions

• Biotherapy
• Chronic Inflammatory Disease
• Allergic Skin Reaction
• Pediatric Disorder
• Dermatologic Complication
• Gastrointestinal Disease
• Ophthalmology
• Rheumatology

Interventions

Type	Name	Description
OTHER	dermatological consultation	Dermatological consultation will be done on every children treated by biotherapy for chronic inflammatory disease in the Amiens hospital.

Timeline

• Start date: 2020-03-12
• Primary completion: 2020-07-01
• Completion: 2020-10-01
• First posted: 2020-03-31
• Last updated: 2021-07-21

Locations

1 site across 1 country: France