NCT04325724

Evaluation of the Role of Inflammatory and Structural Ultrasound Abnormalities by Explaining the Perspective of Patients With Psoriatic Arthritis

Monocentric Cross-sectional Study Assessing the Role of Inflammatory and Structural Ultrasound Abnormalities by Explaining the Perspective of Patients With Psoriatic Arthritis

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Assistance Publique - Hôpitaux de Paris · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The perspective of the patient is defined by the patient reported outcomes (PROs). This is a main part of the care in psoriatic arthritis. However , PROs can be influenced by environmental parameters. Ultrasound represents an objective instrument in the context of psoriatic rheumatism (RhPso) care because it measures inflammatory activity and structural damage at joint and periarticular level. it is the first study to evaluate the role of inflammatory and structural ultrasound abnormalities as a cause of modification of the patient's perspective measured by PROs in patients with RhPso.

Detailed description

It is an interventional study. Patients will be enrolled in the rheumatology department Of Ambroise Paré Hospital in collaboration with the dermatology departments of the hospital. All patients with psoriatic arthritis, beginner or established, or patients with psoriasis suspecting the beginning of rheumatism who will consult or are already followed in those departments and give their approval for the study will undergo * a clinical rheumatologic assessment (number of painful or swollen joints, enthesitic pain, inflammatory spinal pain) * an ultrasound assessment (peripheral joints, tendon and enthesitic structures and nails). Those assessment will be made the same day of their consult in one those departments. They will be asked to complete questionnaires (PROs) on the overall assessment of the disease, pain, quality of life, tiredness, physical limitation / disability and the impact of the disease.

Conditions

• Psoriatic Arthritis

Interventions

Type	Name	Description
OTHER	General evaluation	Demographic characteristic, psoriasis duration, disease duration, treatments
OTHER	Dermatological evaluation	treatment and evaluation
OTHER	Rheumatological evaluation	joints, enthesis, tendons, and other ultrasound abnormalities
OTHER	para clinical data	biological data, medical imaging data
OTHER	Patient reported outcomes (PROs)	Psoriatic arthritis impact of disease 12 (PsAID12), hospital anxiety and depression scale (HAD), SF 36

Timeline

• Start date: 2020-04-01
• Primary completion: 2020-04-01
• Completion: 2020-04-01
• First posted: 2020-03-30
• Last updated: 2020-04-06