NCT04322331

Tumor Immune Mechanism of Axillary Lymph Node Metastasis in Early Luminal Type A Breast Cancer

The Different Transcriptional Characterization Of The Tumor Immune Microenvironment of Luminal A Breast Cancer With Different Lymph Node Metastasas Status

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 120 (actual)
• Sponsor: Peking University People's Hospital · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

Luminal type A breast cancer is a type with good clinical prognosis, and the proportion of lymph node metastasis is low, but a small number of patients have more lymph node metastasis when the primary tumor is very small, and the survival is poor, suggesting that this part of Luminal A breast cancer has the different expression of some genes from that of general Luminal A breast cancer, which affects tumor invasion and participates in the occurrence of tumor metastasis. But the mechanism is not clear, especially in the current tumor microenvironment and immune related mechanisms.We want to investigated the relationship of the transcriptional tumor immune microenvironment with early lymph node metastasis among Luminal A type breast cancer.

Conditions

• Immune Microenvironment
• Luminal A
• Lymph Node Metastases

Interventions

Type	Name	Description
OTHER	no intervention	no intervention

Timeline

• Start date: 2020-05-01
• Primary completion: 2021-05-01
• Completion: 2021-12-31
• First posted: 2020-03-26
• Last updated: 2020-03-31

Locations

1 site across 1 country: China