NCT04320433

Inter-day Reliability of the Oral Glucose Tolerance Test Using Indirect Calorimetry

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Universidad de Granada · Academic / Other
• Sex: All
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

The main aim of this study is to determine the inter-day reliability, by using indirect calorimetry, of the post-prandial macronutrient oxidation and energy expenditure after consuming oral glucose load solution.

Detailed description

The maintenance of blood glucose concentrations and the oxidation of carbohydrate after consuming carbohydrate is related with a low risk of mortality and morbidity from cardiometabolic diseases. The oral glucose tolerance test is a diagnostic test widely used in the clinical field. However, its inter-day reliability has not been deeply studied. Therefore, it is of clinical interest to study the inter-day reliability of the diagnostic test oral glucose tolerance test using indirect calorimetry and monitoring the response of the glucose levels. 20 young adults will undergo two trials visit with 7 days of separation between conditions. Each evaluation day will conform to the following tests: 1. Basal metabolic rate assessment through indirect calorimetry. 2. Basal heart rate variability through heart rate monitor. 3. Intake of the corresponding glucose load solution. 4. Postprandial nutrient oxidation and energy expenditure assessment through indirect calorimetry 5. Glucose monitoring through Glucose meter.

Conditions

• Glucose Intolerance

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Oral glucose tolerance test	Participants will ingest 75g anhydrous glucose dissolved in a volume of 200mL of water (NUTER.TEC GLUCOS, Subra, Toulouse, France).

Timeline

• Start date: 2020-04-01
• Primary completion: 2020-07-01
• Completion: 2020-07-01
• First posted: 2020-03-25
• Last updated: 2020-03-25

Locations

1 site across 1 country: Spain