NCT04320017

Joint Use of Electrocardiogram and Transthoracic Echocardiography With Other Clinico-biological Parameters in an Observational Study to Monitor Cardio-vascular Events and Predict Outcomes in Patients Diagnosed With COVID-19

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 500 (actual)
• Sponsor: Groupe Hospitalier Pitie-Salpetriere · Academic / Other
• Sex: All
• Age: 16 Years
• Healthy volunteers: Not accepted

Summary

COVID-19 outbreak is often lethal. Mortality has been associated with several cardio-vascular risk factors such as diabetes, obesity, hypertension and tobacco use. Other clinico-biological features predictive of mortality or transfer to Intensive Care Unit are also needed. Cases of myocarditis have also been reported with COVID-19. Cardio-vascular events have possibly been highly underestimated. The study proposes to systematically collect cardio-vascular data to study the incidence of myocarditis and coronaropathy events during COVID-19 infection.We will also assess predictive factors for transfer in Intensive Care Unit or death.

Conditions

• COVID-19
• Myocardial Injury
• Myocarditis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Electrocardiogram, transthoracic echocardiography and clinico-biological parameters in routine care	* 12 derivations electrocardiogram done at baseline and repeated every 3 days * transthoracic echocardiography at baseline * clinical features at baseline: WHO performans status comorbidities and treatments * biological results in routine care, such as baseline full blood count, inflammation markers: C-reactive protein, procalcitonin, interleukin-6 and ferritin, coagulation and troponin and brain natriuretic peptide

Timeline

• Start date: 2020-03-20
• Primary completion: 2020-07-20
• Completion: 2020-07-20
• First posted: 2020-03-24
• Last updated: 2023-01-04

Locations

1 site across 1 country: France