NCT04319536

Integrated Genetic and Functional Analysis of the Female Microbiome in a Flemish Cohort

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: University Hospital, Antwerp · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The aim of the project is to improve our knowledge on the stability and temporal dynamics of the Flemish female microbiome (vagina, skin and saliva) in relation to different lifestyle factors and environmental conditions and to establish certain individual and social risk factors that can influence the healthy microbiome. Therefore, microbial DNA from swabs will be isolated via commercially available DNA extraction kits, followed by Illumina MiSeq sequencing in order to identify the microbial species present in these samples. Special attention will go to microbial species that are overrepresented in the healthy populations as potential health promoting microbes (i.e. probiotics).

Conditions

• Vaginal Microbiome
• Skin Microbiome
• Saliva Microbiome

Interventions

Type	Name	Description
OTHER	no intervention	self-sampling

Timeline

• Start date: 2020-03-01
• Primary completion: 2025-07-01
• Completion: 2025-07-01
• First posted: 2020-03-24
• Last updated: 2021-01-27

Locations

1 site across 1 country: Belgium