Clinical Trials Directory

Trials / Completed

CompletedNCT04318080

Tislelizumab in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma

A Phase 2, Multicenter, Open-Label Study of Tislelizumab (BGB-A317) in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
46 (actual)
Sponsor
BeiGene · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This was a Phase 2 trial evaluating the effectiveness and safety of tislelizumab in participants with relapsed or hard-to-treat classical Hodgkin lymphoma (cHL). Participants were grouped by prior treatments. The main outcome was to assess overall response rate (ORR) across both cohorts. Participants continued receiving the study treatment until their disease got worse, side effects became too severe, or they chose to stop for other reasons.

Conditions

Interventions

TypeNameDescription
DRUGTislelizumab200 milligrams (mg) intravenously every 3 weeks (Q3W)

Timeline

Start date
2020-08-20
Primary completion
2022-12-12
Completion
2024-08-29
First posted
2020-03-23
Last updated
2025-09-24
Results posted
2025-09-24

Locations

4 sites across 2 countries: United States, Australia

Regulatory

Source: ClinicalTrials.gov record NCT04318080. Inclusion in this directory is not an endorsement.