NCT04317183

Topical Chamomile in Preventing Chemotherapy-induced Oral Mucositis

The Effect of Topical Chamomile in the Prevention of Chemotherapy-induced Oral Mucositis (a Randomized Controlled Clinical Trial)

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 45 (estimated)
• Sponsor: Hams Hamed Abdelrahman · Academic / Other
• Sex: All
• Age: 20 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

the main aim of this study is to clinically assess the effectiveness of topical chamomile oral gel in the prevention of chemotherapy-induced oral mucositis.

Detailed description

The study was designed as a randomized, controlled, clinical trial. patients who were undergoing to receive chemotherapy were divided into three groups: Group I: was given conventional treatment. Group II: was given topical oral gel of chamomile. Group III: was given topical oral gel of chamomile in combination with the conventional treatment. All patients have clinically evaluated at the start of the chemotherapy and three weeks later for pain and oral mucositis severity.

Conditions

• Oral Mucositis Due to Chemotherapy

Interventions

Type	Name	Description
DRUG	chamomile topical oral gel	Chemical constituents of chamomile, such as bisabolol, chamazulene, and the flavonoids apigenin and luteolin, possess anti-inflammatory properties.
DRUG	Miconazole Topical Gel	topical anti fungal agent
DRUG	BBC oral spray	Topical anesthetics and anti-inflammatory agent
DRUG	Oracure gel	Topical analgesic gel

Timeline

• Start date: 2019-05-15
• Primary completion: 2020-03-15
• Completion: 2020-03-30
• First posted: 2020-03-23
• Last updated: 2020-03-23

Locations

1 site across 1 country: Egypt