NCT04315740

Acute Health Effects Due to Ultrafine Particles From Candles and Cooking

THE ULTRAFINE PROJECT - A Study of Acute Health Effects of Exposure to Particles Generated by Candles and Cooking

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: University of Aarhus · Academic / Other
• Sex: All
• Age: 15 Years – 25 Years
• Healthy volunteers: Accepted

Summary

People spend up to 90% of their life indoor, and the way we live and behave in our homes has substantial effects on our health and well-being. Particle contamination is suggested to have substantial negative effects on health, with candles and cooking emitting the largest amount of particles, thus being the largest contributors to indoor air pollution. The overall aim of the present project is to contribute to increased understanding of the association between indoor particulate air pollution and health and well-being.

Detailed description

Introduction: People spend up to 90% of their life indoor, and the way we live and behave in our homes has substantial effects on our health and well-being. Particle contamination is suggested to have substantial negative effects on health, with candles and cooking emitting the largest amount of particles, thus being the largest contributors to indoor air pollution. Little is known about the potential adverse health effects of candles and cooking, and people with asthma may be more susceptible. Aim: To investigate local and systemic effects of short-term exposure to lit candles and cooking among young asthmatics. Design: In a randomised double-blinded cross-over study non-smoking asthmatics (18-25 years) were exposed for five hours at three different exposure conditions separated by 14 days; A) clean filtered air, B) lit candles and C) cooking emissions under controlled environmental conditions. Measurements: TSI P-TRAK Ultrafine Particle Counter was used for particle counts. Health effects, including lung function (FEV1/FVC) and fraction of exhaled nitric oxide (FeNO) were evaluated in relation to local and systemic effects prior to, right after and 24 h. after exposure. Analysis: Mixed methods approach taking both time and exposure into account.

Conditions

• Candle Burning
• Cooking
• Lung Function Decreased
• DNA Damage
• Subjective Health
• Asthma

Interventions

Type	Name	Description
OTHER	Particles from candles	Generating fine and ultrafine particles from lit candles
OTHER	Particles from cooking	Generating fine and ultrafine particles from frying pork in an oven
OTHER	Clean Air	Nothing but clean air

Timeline

• Start date: 2019-04-01
• Primary completion: 2019-12-20
• Completion: 2019-12-20
• First posted: 2020-03-19
• Last updated: 2020-11-06

Locations

1 site across 1 country: Denmark