NCT04315532

The Effect of Periodontal Treatment on Stress and Pregnancy Relationship

Relationship of Sex Steroid and Stress Markers in Saliva and Gingival Crevicular Fluid With Pregnancy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 84 (actual)
• Sponsor: Tokat Gaziosmanpasa University · Academic / Other
• Sex: Female
• Age: 24 Years – 50 Years
• Healthy volunteers: Accepted

Summary

There is a relationship between stress and pregnancy gingivitis. This relationship may be double-sided.

Detailed description

The aim of this clinical study was to determine the effect of non-surgical mechanical periodontal treatment on sex steroid and stress markers at pregnancy gingivitis. A total of 84 subjects; 22 pregnant women with gingivitis (group 1) and 25 pregnant women with periodontal healthy (pregnant group), group 2), 22 non-pregnant women with gingivitis (group 3) and 15 non-pregnant women with periodontal healthy (non-pregnant group), group 4) participated in this study. Clinically, plaque index, gingival index, and probing pocket depth were measured at baseline and after therapy.

Conditions

• Pregnancy Gingivitis

Interventions

Type	Name	Description
OTHER	Non-surgical periodontal treatment	Non-surgical periodontal treatment was performed for pregnant and non-pregnant gingivitis patients. Gingival crevicular fluid (GCF) and saliva samples were taken from all patients baseline and after 8 weeks.
OTHER	Saliva samples	Saliva samples were taken from patients for the evaluation of sex steroid and stress markers baseline and after 8 weeks.
OTHER	GCF samples	GCF samples were taken from patients for the evaluation of stress markers baseline and after 8 weeks.

Timeline

• Start date: 2016-04-01
• Primary completion: 2016-10-01
• Completion: 2016-11-01
• First posted: 2020-03-19
• Last updated: 2020-03-23