Trials / Completed
CompletedNCT04312542
Systemic Markers of Inflammation: 9- and 12-Month Follow-Up Post Non-Surgical Periodontal Therapy
Systemic Markers of Inflammation: 9- and 12-Month Follow-Up Post Non-Surgical Periodontal Therapy With and Without Minocycline HCl Microspheres, 1mg
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 60 (actual)
- Sponsor
- University of Minnesota · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The primary goal of this study is to determine the amount of three systemic markers of inflammation: 1) Hemoglobin A1c (Hgb A1c, 2) High Sensitivity C-Reactive Protein (hsCRP), and 3) Haptoglobin (Hp) at 9 and 12 month follow-up post scaling and rootplaning (SRP) with and without minocycline HCl microspheres, 1 mg.
Detailed description
Participants from a randomized controlled clinical trial approved by the University of Minnesota (UMN) Institutional Review Board (IRB) STUDY00004876 and registered on ClinicalTrials.gov (NCT03762915) identifying the effects of SRP with and without minocycline HCl microspheres, 1 mg on periodontal pathogens and systemic inflammatory markers in the blood serum will be invited to participate in this 9 and 12 month follow-up study.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Measurement of Biomarkers | Participants will have blood drawn at a 9-month and 12-month visit for the measurement of biomarkers. |
Timeline
- Start date
- 2020-07-21
- Primary completion
- 2022-08-16
- Completion
- 2022-08-16
- First posted
- 2020-03-18
- Last updated
- 2022-09-23
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT04312542. Inclusion in this directory is not an endorsement.