Trials / Completed
CompletedNCT04311749
Expanded NIPT for Pregnancy Complications
The Role of Expanded Panel Non-Invasive Prenatal Testing in Identifying Rare Autosomal Trisomies in Pregnancies With Placentally-Mediated Complications
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 70 (actual)
- Sponsor
- University of California, San Francisco · Academic / Other
- Sex
- Female
- Age
- 18 Years – 60 Years
- Healthy volunteers
- —
Summary
This study evaluates the utility of expanded panel non-invasive prenatal testing (NIPT) in detecting confined placental mosaicism of rare autosomal trisomies among pregnancies with placentally-mediated complications, including fetal growth restriction and severe preeclampsia.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | Expanded panel cell free DNA testing (non-invasive prenatal testing) | Maternal blood sampling |
| GENETIC | Placental biopsy | Post-delivery placental sampling |
| GENETIC | Umbilical cord blood | Post-delivery umbilical cord blood sampling |
Timeline
- Start date
- 2020-02-12
- Primary completion
- 2024-06-30
- Completion
- 2024-08-30
- First posted
- 2020-03-17
- Last updated
- 2024-10-18
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT04311749. Inclusion in this directory is not an endorsement.