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CompletedNCT04311034

A Study of RC48-ADC in Subjects With Advanced Non-small Cell Lung Cancer

A Phase Ib Study to Evaluate the Efficacy and Safety of RC48-ADC for Injection in Subjects With Advanced Non-small Cell Lung Cancer With HER2 Overexpression or HER2 Mutation

Status
Completed
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
37 (actual)
Sponsor
RemeGen Co., Ltd. · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This study will evaluate the efficacy and safety of RC48-ADC for injection in subjects with advanced non-small cell lung cancer with HER2 overexpression or HER2 mutation.

Conditions

Interventions

TypeNameDescription
DRUGRC48Participants will be treated with RC48-ADC at a dose of 2.0 mg/kg, every 2 weeks. They will continue the medication until one of the following conditions occurred: disease progression, intolerance of toxicity, investigators believed that the subject could no longer benefit from treatment, or this study ended.

Timeline

Start date
2018-09-26
Primary completion
2021-12-21
Completion
2022-05-30
First posted
2020-03-17
Last updated
2023-12-18

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04311034. Inclusion in this directory is not an endorsement.

A Study of RC48-ADC in Subjects With Advanced Non-small Cell Lung Cancer (NCT04311034) · Clinical Trials Directory