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UnknownNCT04310657

mNGS Was Applied to the Study of Pathogen Identification, Precision Medication and Efficacy Evaluation of Infected Patients

Status
Unknown
Phase
N/A
Study type
Interventional
Enrollment
200 (estimated)
Sponsor
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine · Academic / Other
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

1\) prospectively collected the patients with the proposed infection, confirmed the infection or excluded the infection through mNGS detection combined with traditional pathogen detection methods and clinical characteristics, compared the detection performance of mNGS and traditional methods, and explored the significance of mNGS microbial map characteristics for the diagnosis/exclusion of infection; 2) real-time dynamic monitoring of the pathogen and microecology of infected patients during the targeted drug use, and evaluation of the efficacy in combination with other indicators; 3) to explore the significance of the number of pathogen sequences before the clinical withdrawal of drugs to the clinical practice.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTmNGSMetagenomics second generation sequencing technology

Timeline

Start date
2020-10-01
Primary completion
2023-09-30
Completion
2023-09-30
First posted
2020-03-17
Last updated
2020-03-17

Source: ClinicalTrials.gov record NCT04310657. Inclusion in this directory is not an endorsement.