Trials / Unknown
UnknownNCT04310618
Mucus Solids Concentration in Patients With Bronchiectasis
Characterization of Mucus Solids Concentration in Patients With Bronchiectasis: Cross-sectional Study
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 36 (estimated)
- Sponsor
- Universidad San Jorge · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
There is a need for biomarkers that can rapidly and sensitively detect therapeutic benefits of therapies designed to "rehydrate" airways and monitor disease severity and progression. In this study the investigators will evaluate the stability of mucus concentration in patients with bronquiectasis (CF and NCBF) and its ability to respond to acute exacerbations in order to assess whether it can be a good candidate for biomarker.
Detailed description
Prospective cross-sectional study of repeated measurements. The recruitment will be performed in 3 different cities of Spain: Zaragoza, Barcelona and Murcia. Subjects will be asked to repeatedly collect spontaneous and induced sputum samples in both stable and exacerbated conditions. All samples will be collected autonomously by patients in their homes after they have been instructed and supervised. Hypertonic saline nebulization will be used for sputum induction.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | No intervention | No intervention |
Timeline
- Start date
- 2020-12-21
- Primary completion
- 2023-03-01
- Completion
- 2023-08-01
- First posted
- 2020-03-17
- Last updated
- 2021-10-01
Locations
1 site across 1 country: Spain
Source: ClinicalTrials.gov record NCT04310618. Inclusion in this directory is not an endorsement.