NCT04306874

Whipple Protein Study

High-Protein Oral Nutritional Supplementation in Patients Undergoing Pancreaticoduodenectomy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: Thomas Jefferson University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Study investigators aim to assess the effect of providing high-protein nutritional supplementation before and after surgery

Detailed description

Pancreaticoduodenectomy (PD) is a complex and morbid operation that is associated with many potential complications. Many people undergoing PD are malnourished due to their underlying medical condition or difficulties eating in the face of abdominal pain or obstruction from pancreatic disease. This study aims to assess the effect of high-protein dietary supplementation in improving perioperative nutrition and decreasing complications. We will randomize PD patients to an experimental arm in which they take a nutritional, high-protein supplement for 2 weeks before and after surgery, or to a control arm, where they will take a standard postoperative diet without supplementation. Outcomes and nutritional parameters will be examined after they complete the supplements.

Conditions

• Pancreatic Cancer
• Malnutrition

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Ensure Max Protein	Liquid shake with 30 g protein per serving

Timeline

• Start date: 2019-08-20
• Primary completion: 2022-05-10
• Completion: 2022-11-15
• First posted: 2020-03-13
• Last updated: 2025-05-07

Locations

1 site across 1 country: United States