NCT04305821

Medico-economic Interest of the Protein S100b in Mild Head Trauma Under Anti-thrombotics

Intérêt de la protéine S100β Dans Les Traumatismes Crâniens légers Sous Anti-Thrombotiques

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 260 (actual)
• Sponsor: Rennes University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

Head trauma is a common injury in emergency department. Investigation to search for complication is guided by the clinical examination and the case history, such as taking anti-thrombotics. Cranial computed tomography (CCT) is the gold standard to investigate, and is mandatory in case of antithrombotic drugs. Recently, some biomarkers have proven their utility to rule-out mild head trauma without CCT in the general population. Among these biomarkers, S100β protein has been added in guidelines for mild head trauma. Some studies have found similar data in population taking anticoagulant or antiplatelet drugs. The investigators aim to prove medical utility of S100β protein in population under antithrombotics, by the reduction of CCT use. Then, The investigators hypothesize that the add of S100β protein reduces cost of health care in the management of head injury in that population.

Conditions

• Mild Head Injury
• Anticoagulant
• Antiplatelet

Interventions

Type	Name	Description
OTHER	Dosage of S100β protein	Dosage of S100β protein

Timeline

• Start date: 2020-03-09
• Primary completion: 2021-09-20
• Completion: 2021-09-20
• First posted: 2020-03-12
• Last updated: 2023-04-12

Locations

1 site across 1 country: France