NCT04304885

Effect of Sonication on Periprosthetic Joint Infection Treatment Strategy.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 56 (estimated)
• Sponsor: Bezmialem Vakif University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

It is not known in the literature how much sonication affects the patient's treatment. Another important issue is that the place of this method in diagnosis is not clear. The aim of this study is to contribute to the literature on this issue and to determine the sensitivity and specificity of sonication prospectively using the new definition and effect of sonication on the treatment strategy in terms of infection in patients with PJI.

Detailed description

Total knee and hip arthroplasties are successful surgical procedures that are widely applied all over the world and provide high patient satisfaction and increased quality of life. Periprosthetic joint infection (PJI), is a serious complication that negatively affects the targeted result, decreases patient satisfaction, and increases morbidity and mortality after total joint replacement. Another important issue, the previous infection is the most important reason for the failure of surgery in revision arthroplasty. It is known that the success of PJI treatment seriously can be affected by the type of microorganism and antibiotic sensitivity. Therefore, microbiological examination methods are always of interest, and one of them is the sonication method.

Conditions

• Prosthesis-Related Infections
• Hip Prosthesis Infection
• Joint Infection
• Biofilm

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Sonication method	Sonication dislodges adherent bacteria from explanted prosthetics by ultrasound and may improve the diagnosis of periprosthetic joint infection.

Timeline

• Start date: 2020-03-15
• Primary completion: 2021-01-15
• Completion: 2021-01-15
• First posted: 2020-03-12
• Last updated: 2021-01-07

Locations

1 site across 1 country: Turkey (Türkiye)