Clinical Trials Directory

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UnknownNCT04302519

Novel Coronavirus Induced Severe Pneumonia Treated by Dental Pulp Mesenchymal Stem Cells

Clinical Study of Novel Coronavirus Induced Severe Pneumonia Treated by Dental Pulp Mesenchymal Stem Cells

Status
Unknown
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
24 (estimated)
Sponsor
CAR-T (Shanghai) Biotechnology Co., Ltd. · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

Evaluation of novel coronavirus induced severe pneumonia by dental pulp mesenchymal stem cells

Detailed description

Open, single center, single arm test design. Plan to enroll 24 subjects. On the basis of clinical standard treatment, the injection of dental mesenchymal stem cells was increased on day 1, 3 and 7 of the trial. Injection dose: 1.0x106 cells /kg. Injection method: slowly and quietly drop 50 mL of normal saline, then the endodontic mesenchymal stem cell injection (after 60 min), and then 50 mL of normal saline.

Conditions

Interventions

TypeNameDescription
BIOLOGICALDental pulp mesenchymal stem cellsOn the basis of clinical standard treatment, the injection of dental mesenchymal stem cells was increased on day 1, 3 and 7 of the trial.

Timeline

Start date
2020-03-05
Primary completion
2021-06-30
Completion
2021-07-30
First posted
2020-03-10
Last updated
2020-03-10

Source: ClinicalTrials.gov record NCT04302519. Inclusion in this directory is not an endorsement.