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UnknownNCT04300608

Measures of Mitochondria Dysfunction in PD

Functional and Metabolomic Biomarkers of Mitochondrial Dysfunction in Parkinson's Disease

Status
Unknown
Phase
Study type
Observational
Enrollment
30 (estimated)
Sponsor
University of Washington · Academic / Other
Sex
All
Age
65 Years – 85 Years
Healthy volunteers

Summary

This study evaluates metabolic and functional parameters in the skeletal muscle of Parkinson's disease patients for comparison to a set of healthy age-matched controls.

Detailed description

The goal of this study is to identify the unique signature of bioenergetic markers and mitochondrial (dys)function in muscle of individuals with PD, who are 65-85 of age, read and speak English, have a Hoehn \& Yahr score between 2 and 3 (bilateral disease, not severely disabled) and have a clinical diagnosis of PD. Bioenergetic markers and muscle functional properties will be compared to a control dataset collected over the last few years from healthy elderly subjects in the same age range to provide a foundation for future intervention studies.

Conditions

Timeline

Start date
2020-02-24
Primary completion
2021-07-01
Completion
2021-11-01
First posted
2020-03-09
Last updated
2020-11-05

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT04300608. Inclusion in this directory is not an endorsement.

Measures of Mitochondria Dysfunction in PD (NCT04300608) · Clinical Trials Directory