NCT04297176

Economic Evaluation of Vancomycin Therapeutic Drug Monitoring Methods

Clinical and Economic Evaluation of Optimal Monitoring Parameters and Sampling Schemes for Vancomycin Therapeutic Drug Monitoring in Qatar

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 65 (actual)
• Sponsor: Hamad Medical Corporation · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Vancomycin is a widely used antibiotic in the treatment of complicated gram positive infections. Approaches to vancomycin therapeutic drug monitioring (TDM) vary. This clinical trial aimed to compare the pharmacoeconomic outcomes between various vancomyicn TDM approaches. Research questions: Which vancomycin therapeutic drug monitoring (TDM) approach is associated with superior economic outcomes? -Objectives: In this proposed multicenter randomized controlled trial (RCT), we aim to compare the pharmacoeconomic outcomes of various vancomycin TDM approaches.

Conditions

• Infection, Bacterial

Interventions

Type	Name	Description
DRUG	Vancomycin-traditional dosing	The dose is calculated based on 2 vancomycin serum levels
DRUG	Vancomycin- Trough-only based dosing	The dose is calculated based on 1 vancomycin serum level (i.e. trough)

Timeline

• Start date: 2020-01-23
• Primary completion: 2021-05-04
• Completion: 2021-07-02
• First posted: 2020-03-05
• Last updated: 2022-08-15

Locations

1 site across 1 country: Qatar