NCT04293003

Metabolic Effects of Morning 16/8 Fasting

Short-term Metabolic Effects of Morning Energy Restriction Versus Two Different Early-day Nutrition Strategies

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: National and Kapodistrian University of Athens · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

A study to address the effects of early-day fasting on fat tissue mobilization in comparison to a typical isocaloric Mediterranean and a low-carbohydrate breakfast.

Detailed description

The study design meets a cross-over pattern with 3 different morning visits of 6 hour duration each. After an informed consent is received from the participant, a crude medical history, physical examination and collection of somatometric data through bio-impendance analysis will take place. An intravenous catheter will be placed in the participants forearm. At zero time point, depending on study visit, participants will either (A) remain fasted (B) start consuming ta pre-prepared zero-carbohydrate 500 kcal test meal (C) start consuming ta pre-prepared 500 kcal test meal with a composition conforming to a standard Mediterannean breakfast. Participants will be given 10 minutes to consume the meal. Blood samples will be drawn and visual analogue scales (VAS) for hunger and satiety will be filled in at the following time points (min): -15, 0, 15, 30, 60, 90, 120, 180, 240, 300, 360.

Conditions

• Overweight and Obesity

Interventions

Type	Name	Description
OTHER	fasting	6-hour fasting
OTHER	Low carbohydrate	Consumption of a zero-carbohydrate breakfast
OTHER	Mediterranean	Consumption of a Mediterranean-type breakfast

Timeline

• Start date: 2020-01-07
• Primary completion: 2020-02-29
• Completion: 2020-02-29
• First posted: 2020-03-03
• Last updated: 2020-03-19

Locations

1 site across 1 country: Greece