NCT04292236

The Effect of Food Supplements on Food Intake and Gut Hormone Levels

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Queen Mary University of London · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

When a meal is eaten, nutrients activate the release of hormones from the bowel into the blood stream. Normally there is a large amount of hormone released, which tells the brain that an individual is full and to stop eating. When people gain weight and become overweight or obese, these hormone signals are reduced, resulting in these people eating more and gaining more weight. This study is investigating mechanisms which may break this cycle by using particular nutrients to restore reduced hormone levels.

Conditions

• Obesity
• Endocrine; Obesity
• Appetite; Perverted

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Lauric Acid, Perilla Oil and Diindolylmethane	Colonic release capsules containing lauric acid (2400mg), perilla oil (2100mg) and diinodlylmethane (500mg) given to volunteers 1 hour prior to standardised breakfast and lunch meal. Placebo group given cellulose capsules of same volume prior to standardised breakfast and lunch meal.

Timeline

• Start date: 2019-02-22
• Primary completion: 2019-07-22
• Completion: 2019-07-22
• First posted: 2020-03-03
• Last updated: 2020-03-03

Locations

1 site across 1 country: United Kingdom